contraindication

KON-truh-in-duh-KAY-shuhn /ˌkɑːntrəˌɪndɪˈkeɪʃn/
nounC1GRETOEFL
formaltechnical

A specific situation, condition, or factor that serves as a reason to withhold a particular pharmaceutical or medical treatment due to the harm it would cause.

Implies a medical danger or conflict between a therapy and a patient's pre-existing state, rather than just a mild side effect.

The story behind the word. Formed from Latin 'contra-' (against) and 'indicare' (to point out or indicate). The term gained formal adoption in 19th-century clinical literature to denote physiological flags that indicated a treatment should NOT be used.

Word relationships

  • red flag: Red flag is an informal term for a warning signal, whereas contraindication is a precise medical terms for clinical prohibition.
  • indication: An indication is a valid clinical reason or sign to prescribe a specific medication or procedure.

Commonly confused with

  • side effect: A side effect is an secondary outcome caused by taking a drug, whereas a contraindication is a condition that forbids taking the drug in the first place.

Word family

  • contraindicate (verb): To advise against a specific treatment due to potential harm.

Collocations

  • absolute contraindication
  • relative contraindication
  • major contraindication
  • contraindication to therapy

Example sentences

  • "Severe renal impairment represents an absolute contraindication for the use of this contrast dye." Medical Assessment
  • "Pregnancy is a well-known contraindication for live attenuated vaccines due to potential risks to the fetus." Clinical Guidance

Memory hook

CONTRA (against) + INDICATION (pointing to a fix) = Pointing AGAINST using a drug. Contraindication = A reason to STOP and NOT prescribe.

When not to use

Do not use 'contraindication' for a general inconvenience or personal dislike; it refers strictly to medical risk factors.

Fun facts

  • In clinical medicine, contraindications are classified as either 'absolute' (never give the drug under any circumstance) or 'relative' (weigh risks versus benefits carefully).

Related words

adverse, toxicity, dosage

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