splicing

SPLY-sing /ˈsplaɪsɪŋ/
nounverbC1GRETOEFL
technicalscientific

The process of joining or connecting different pieces of DNA or RNA.

In genetics, it specifically refers to removing non-coding regions (introns) or combining genes from different sources.

The story behind the word. Originally a nautical term from the 16th century, 'splicing' referred to joining two ropes by interweaving their strands. Geneticists borrowed the term to describe the interweaving of DNA strands.

Word relationships

  • recombination: Recombination is a broader biological process; splicing is the specific act of cutting and joining.
  • cleavage: Refers to the splitting or cutting of DNA without the subsequent joining.

Commonly confused with

  • splitting: Splitting is just breaking apart; splicing is joining together (often after a cut).

Word family

  • splice (verb): To join or connect.

Collocations

  • gene splicing
  • alternative splicing
  • splicing enzymes

Example sentences

  • "Gene splicing allows researchers to insert a pest-resistance gene directly into a corn plant's DNA." Explaining the mechanism of gene editing.
  • "The movie depicted a future where gene splicing had created strange new hybrid creatures." A classic science fiction reference.

Memory hook

Think of 'splicing' film together in an old movie projector to create a new scene. Cut and paste DNA.

When not to use

Not used for simple mixing; it implies a precise physical or chemical joining.

Fun facts

  • Alternative splicing allows a single gene to code for multiple proteins, making complex life possible.

Related words

modification, engineered

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