mutation

myoo-TAY-shun /mjuːˈteɪʃən/
nounC1GRESAT
FormalScientific

The changing of the structure of a gene, resulting in a variant form that may be transmitted to subsequent generations, caused by the alteration of single base units in DNA, or the deletion, insertion, or rearrangement of larger sections of genes or chromosomes.

Can be spontaneous or induced, and can be beneficial, harmful, or neutral in its effect on an organism's survival and reproduction.

The story behind the word. 'Mutation' comes from the Latin mutare, meaning 'to change.' In biology, the term was popularized by Dutch botanist Hugo de Vries in the early 20th century to describe sudden, heritable changes in organisms, which he observed in evening primroses. These changes were distinct from the continuous variation seen in populations.

Word relationships

  • genetic alteration: More formal and descriptive.
  • genetic change: Simpler and more direct.
  • stability: Absence of change.
  • conservation: Preservation of original form.

Word family

  • mutate (verb): To change or cause to change in form or nature.
  • mutant (noun): An organism or a new character resulting from an alteration of a gene or chromosome.

Collocations

  • gene mutation
  • point mutation
  • silent mutation
  • random mutation
  • beneficial mutation

Example sentences

  • "A random mutation in a single gene can sometimes lead to a new trait, which may or may not be advantageous." Explaining genetic variation.
  • "Harmful mutations are often eliminated by natural selection, while beneficial ones can become more common over generations." Discussing evolutionary processes.

Memory hook

A 'mutation' causes a 'MUtation' (a change) in the genetic code. Genetic change.

When not to use

Don't use 'mutation' to describe a general change or transformation; it specifically refers to a genetic alteration. For example, a car changing color is not a mutation.

Fun facts

  • Most mutations are neutral, meaning they have no significant effect on an organism.
  • The ability of bacteria to develop antibiotic resistance is a result of beneficial mutations.

Related words

gene, evolution

Explore more words

genetics, genetic, mutable

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